The histopathological and immunohistochemical diagnosis in small cell lung carcinoma

Vol. 45 No. Cumulative Issue 1999-2004, 2004

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Ana-Maria Dragan, G. Simu, T. Vaida

The small cells lung carcinoma (SCLC) represents 10-25% of the bronchogenical carcinomas, prevails at middle ages and is closely associated with tobacco smoke. It belongs to the group of carcinomas with neuroendocrine differentiation, the patients presenting various paraneoplasic syndromes. The study was performed on 491 patients with a clinical and radiological suspicion of bronchopulmonary cancer. In this study, the histopathological examination gives results similar to those mentioned in the medical literature for the small cells lung carcinoma, prevailing in the case of young patients. The immunohistochemical examinations are particularly precious in confirming the diagnosis, especially in the diagnosis of the lymphonodular micrometastases.

Corresponding author: Ana-Maria Dragan, MD, PhD, e-mail: dragan_21_noiembrie@yahoo.com

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